Yesterday (Sun., September 14, 2014) injuries hit the NFL harder than nearly any other week in history. Several elite players were forced out of their games and will require several weeks to recoup.

Lets’ take a look at some of the most high profile and damaging injuries from Week 2.

Kansas City Chiefs running back Jamaal Charles was forced out of his team’s 24-27 loss to the Denver Broncos with an ankle injury. Initial reports stated that Charles’ sprain was of the mild variety, but an MRI revealed that he might have the dreaded high ankle sprain.

Chiefs reporter BJ Kissel reported that it might not be all that serious, however:

“It doesn’t look to be a real severe one, but it does have the component of a high ankle sprain.” #Chiefs coach Andy Reid on Jamaal Charles

— BJ Kissel (@ChiefsReporter) September 15, 2014

After getting off to by far the best start of his career, New Orleans Saints running back Mark Ingram unfortunately broke his hand in the team’s Week 2 loss to the Cleveland Browns and will be out for around a month.

Arizona Cardinals quarterback Carson Palmer was forced out Arizona’s Week 2 win over The New York Giants with a shoulder issue that apparently involves nerves. Cardinals coach Bruce Arians expressed concern about the injury to reporter Darren Urban today:

Arians on Palmer’s injury: “Anytime you’re dealing with nerves, you’re concerned.”

— Darren Urban (@Cardschatter) September 15, 2014

In a rarely- seen bit of positive injury news, Tampa Bay Buccaneers running back Doug Martin would have apparently practiced if the team did so today. According to Rick Stroud, Martin could be in play for the team’s Thursday Night game against the Atlanta Falcons:

#Bucs Smith said only 3 players would not have been able to practice today, which means Doug Martin is in play for Thursday night.

— Rick Stroud (@NFLSTROUD) September 15, 2014

Finally, San Francisco 49ers tight end Vernon Davis left his team’s devastating loss to Chicago last night with an ankle injury. CSN’s Matt Maiocco stated that coach Jim Harbaugh confirmed that Davis was headed for an MRI and it is feared he may also have a high ankle sprain:

Jim Harbaugh: 49ers TE Vernon Davis is undergoing MRI on left ankle.

— Matt Maiocco (@MaioccoCSN) September 15, 2014

All in all, it was a terrible weekend for injuries that has decimated several rosters of top talent. Stay tuned to TSM Plug for more NFL updates as they arise.